Do not use if you have high blood pressure if you are taking health products that affect blood coagulation (blood thinners, clotting factor replacements, acetylsalicylic acid, ibuprofen, fish oils, vitamin E) as this may increase the risk of spontaneous bleeding. Consult a healthcare practitioner prior to use if symptoms persist or worsen if you have any type of acute infection if you are taking medications for diabetes, seizures, or antidepressant medications, if you are taking blood thinners or digoxin and if you have diabetes, cardiovascular disease, ulcers, melanomas, nervous disorders, Parkinson's disease or psychosis. Hypersensitivity/allergy has been known to occur- if this occurs discontinue use. Consumption of alcohol, other drugs or natural health products with sedative properties is not recommended.